To help make backing out of a parking space safer, the 5 Series has standard Cross Traffic Warning with Brake Intervention, systems which detect vehicles approaching from the sides and can automatically apply the brakes to prevent a collision. Rear Cross-Traffic Braking costs extra on the ES.
Both the 5 Series and the ES have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, front seatbelt pretensioners, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, post-collision automatic braking systems, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors, available all wheel drive and around view monitors.
Side impacts caused 23% of all road fatalities in 2018, down from 29% in 2003, when the Insurance Institute for Highway Safety introduced its side barrier test. In order to continue improving vehicle safety, the IIHS has started using a more severe side impact test: 37 MPH (up from 31 MPH), with a 4180-pound barrier (up from 3300 pounds). The results of this newly developed test demonstrates that the BMW 5 Series is safer than the ES:
|   
  | 
     5 Series  | 
     ES  | 
  
|   Overall Evaluation  | 
     GOOD  | 
     ACCEPTABLE  | 
  
|   Structure  | 
     GOOD  | 
     ACCEPTABLE  | 
  
|   
  | 
     Driver Injury Measures  | 
  |
|   Head/Neck  | 
     GOOD  | 
     GOOD  | 
  
|   Head Injury Criterion  | 
     193  | 
     403  | 
  
|   Neck Tension  | 
     245 lbs.  | 
     312 lbs.  | 
  
|   Neck Compression  | 
     67 lbs.  | 
     89 lbs.  | 
  
|   Torso  | 
     ACCEPTABLE  | 
     ACCEPTABLE  | 
  
|   Shoulder Deflection  | 
     1.1 in  | 
     1.54 in  | 
  
|   Shoulder Force  | 
     268 lbs.  | 
     379 lbs.  | 
  
|   Torso Max Deflection  | 
     1.26 in  | 
     1.38 in  | 
  
|   Pelvis  | 
     ACCEPTABLE  | 
     ACCEPTABLE  | 
  
|   Head Protection  | 
     GOOD  | 
     GOOD  | 
  
|   
  | 
     Passenger Injury Measures  | 
  |
|   Head/Neck  | 
     GOOD  | 
     GOOD  | 
  
|   Head Injury Criterion  | 
     158  | 
     197  | 
  
|   Neck Tension  | 
     89 lbs.  | 
     134 lbs.  | 
  
|   Torso  | 
     GOOD  | 
     GOOD  | 
  
|   Torso Deflection Rate  | 
     7 MPH  | 
     10 MPH  | 
  
|   Pelvis  | 
     GOOD  | 
     MARGINAL  | 
  
|   Pelvis Force  | 
     803 lbs.  | 
     1205 lbs.  | 
  
|   Head Protection  | 
     GOOD  | 
     GOOD  | 
  

